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Risonanza magnetica sagittale con evidenziazione della posizione del cingolato posteriore

Posterior cingulate cortex

Written by Andrea Pintimalli - Redazione scientifica on .

The posterior cingulate cortex (PCC) is a belt-shaped area located behind the cingulate cortex in the brain, surrounding the corpus callosum. The posterior cingulate cortex is known to be involved in self-awareness and in the management of memories associated with pain. Activation of the PCC occurs when autobiographical memories are recalled and when familiar faces are perceived. The posterior cingulate cortex (PCC) and the hippocampus are the brain regions showing the greatest reduction in metabolic activity in Alzheimer’s disease. These pathological brain lesions are dissociated from those observed during normal aging, which is characterized by atrophy of the frontal lobes.

 

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Bibliography
  • R Leech; R Braga; DJ Sharp (2012). “Echoes of the brain within the posterior cingulate cortex”. The Journal of Neuroscience. 32 (1): 215–222. doi:10.1523/JNEUROSCI.3689-11.2012
  • Maddock, Richard J.; Garrett, Amy S.; Buonocore, Michael H. (January 2003). “Posterior cingulate cortex activation by emotional words: fMRI evidence from a valence decision task”. Human Brain Mapping. 18 (1): 30–41. doi:10.1002/hbm.10075
  • Garrison KA, Santoyo JF, Davis JH, Thornhill TA, Kerr CE, Brewer JA (2013). “Effortless awareness: using real time neurofeedback to investigate correlates of posterior cingulate cortex activity in meditators’ self-report”. Front Hum Neurosci. 7: 440. doi:10.3389/fnhum.2013.00440

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