Mental Health
Desolation
INDEX
ToggleDesolation in psychology: when inner emptiness becomes a human experience
Desolation, understood as a psychological state, should not be confused with a simple feeling of sadness or a passing moment of melancholy. It is a deeper, more complex, and pervasive experience that involves self-perception, relationships with others, and the ability to find meaning and direction in life. Scientifically, desolation has been studied in psychology as a condition that can arise following trauma, loss, isolation, or experiences of failure.
From a neurobiological perspective, it is associated with alterations in brain systems linked to emotional processing, particularly hyperactivation of the amygdala"The amygdala is a gray matter structure named after its cha... More and reduced functionality of prefrontal areas responsible for cognitive regulation. At an existential level, desolation represents a sense of emptiness that goes beyond clinical sadness and can lead to phenomena of alienationCi sono momenti in cui il mondo sembra perdere consistenza: ... More, loss of motivationMotivation: a scientific perspective Motivation is a fundame... More, or disconnection from others. To understand its impact, it is useful to consider how this state affects not only the individual dimension but also the social one, as those experiencing desolation often withdraw, reducing their participation in collective life.
What are the psychological characteristics of desolation?
Desolation has distinctive traits that set it apart from more common and transient emotions. It manifests as a state that encompasses the entire psychic experience and can influence both the cognitive and affective dimensions. The main psychological characteristics include:
- Perception of inner emptiness: the person does not feel only sadness but a genuine sense of absence of meaning. It is not the lack of a specific object that generates distress, but the feeling that nothing has value or importance.
- Reduced capacity for emotional connectionConnection: the human need that precedes all technology Conn... More: those experiencing desolation struggle to feel empathyEmpathy is a fundamental skill that allows us to connect wit... More, affectionWhat is affect according to science? Affect represents one o... More, or authentic closeness with others. This inner isolation can lead to progressive social withdrawal.
- Motivational block: daily activities, even those that were previously sources of pleasure or interest, lose their appeal. This results in a general slowdown of initiatives, with risks of existential stagnation.
- Negative hyper-reflection: desolation is often accompanied by recurring thoughts focused on failure, loss, or the uselessness of one’s existence. This mental attitude, similar to depressive rumination, amplifies suffering.
- Related physiological alterations: insomnia, lack of energy, and somatic tensions can reinforce the psychological state, creating a vicious cycle that is hard to break.
These elements make desolation a state difficult to overcome spontaneously and, in some cases, a precursor to clinical disorders such as major depressionDepression is a disorder characterized by persistent sadness... More.
How does desolation differ from depression?
At first glance, desolation may seem similar to depression, but a closer analysis reveals significant differences with important clinical and social implications. This distinction is not merely theoretical: recognizing the boundaries between depression and desolation allows for better-calibrated therapeutic strategies and support tools. Key differences include:
- Temporality and intensity. Depression is a diagnosable clinical disorder, with specific criteria and symptoms that persist for weeks or months. Desolation, on the other hand, may present as an acute, more fluctuating state, but no less painful.
- Existential origin. While depression is often explained through biological and genetic factors, desolation is more strongly linked to experiences of loss, isolation, or failure on a personal and relational level.
- Depression tends to undermine self-esteemThe term self-esteem literally refers to the evaluation of o... More and basic confidence in one’s abilities, whereas desolation relates more to the overall sense of existence, with profound questions about “why” and “for what” to live.
- Relationship with external reality. Depression often features anhedonia, i.e., loss or reduction in the ability to experience pleasure, interest, or satisfaction in activities that were once rewarding. In desolation, while this dimension may be present, it is accompanied by a strong sense of estrangement and disconnection from the social world.
- Potential for transformation. Desolation, although a source of suffering, has been interpreted by some philosophical and psychological approaches as an opportunity for reflection and reorientation, an existential “turning point.”
What factors can generate desolation?
The state of desolation does not arise from nothing but results from a combination of psychological, social, and existential conditions. Common factors include:
- Traumatic events: the loss of a loved one, job failure, separation, or sudden events that destabilize routine can trigger a sense of emptiness.
- Social isolation: the lack of meaningful relationships is one of the most powerful factors. NeuroscienceThe human brain is one of the most complex and fascinating s... More shows that the absence of social connection activates brain areas associated with physical pain.
- Chronic stressWhat is stress? From a clinical perspective, stress is a phy... More conditions: living under constant pressure without adequate copingCoping is the ability to face and manage stress, challenges,... More resources can lead to inner wear that manifests as desolation.
- Identity or meaning crises: transitional life moments, such as retirement, becoming a parent, or a radical life change, can lead to questioning one’s entire personal orientation.
- Cultural and historical influences: in times of collective uncertainty, such as wars, pandemics, or economic crises, desolation becomes a widespread feeling affecting not just individuals but entire communities.
Analyzing these factors helps understand that desolation is not merely an “individual problem,” but an experience intertwined with social and cultural dynamics.
How does desolation affect daily life?
Desolation has tangible consequences that reflect on functioning in various areas of daily life. Understanding its impact allows for timely recognition and intervention, both preventively and therapeutically. Personally, it can result in a loss of interest in usual activities, difficulty concentrating, and reduced decision-making capacity. Socially, it generates isolation, reduced interpersonal relationships, and a sense of estrangement from one’s group. This detachment can create a vicious cycle: the fewer meaningful relationships are maintained, the stronger the sense of emptiness and abandonmentAbandonment is one of the most intense and complex human exp... More. Even at work, desolation has measurable effects: reduced productivity, absenteeism, and burnoutBurnout is a state of physical, emotional, and mental exhaus... More are often linked to such emotional states.
In terms of health, desolation can have physiological consequences. Scientific research has shown that loneliness and lack of meaning are associated with increased cardiovascular risk, weakened immune system, and higher chronic inflammation levels. Psychologically, it fuels negative thoughts, heightens perceived helplessness, and may lead to self-harming behaviors. A practical example is elderly individuals living alone and deprived of social stimulation, who develop desolation that progressively worsens overall health.
What strategies can help overcome desolation?
Addressing desolation requires targeted interventions that consider its complex nature. There are no single solutions, but a combination of strategies can provide significant support.
- Psychological support: psychotherapy, particularly person-centered and cognitive approaches, helps recognize dysfunctional thoughts and rebuild a more positive self-narrative.
- Social network: cultivating authentic relationships is one of the most effective remedies. Even small daily gestures of connection (a phone call, a meeting, a group activity) can reduce the sense of emptiness.
- Meaningful activities: engaging in projects that restore purpose and meaning, such as volunteeringVolunteering is an activity of help and service carried out ... More or creative hobbies, helps reshape identity.
- Mindfulness and meditationThere are many ways to define meditation, but perhaps the si... More interventions: these practices train the ability to stay present and reduce the hyper-rumination that fuels desolation.
- Body care: balanced nutritionLife does not take breaks: in every living being, bodily fun... More, regular sleep, and physical exercise are essential. Neuroscientific studies show that physical activity stimulates neurotransmitters linked to well-being, such as serotoninSerotonin, also known as 5-hydroxytryptamine (5-HT), is a ne... More.
It is important to emphasize that in some cases, desolation may also require medical intervention, especially if associated with significant depressive or anxious symptoms. The key is not to face it alone, but to build a pathway that integrates psychological, social, and biological dimensions.
Watch the video and discover 3 practices to train your mind
"*" indicates required fields

GUIDED MEDITATIONS
- Boreham, I. D., & Schutte, N. S. (2023). The relationship between purpose in life and depression and anxietyAnxiety is an emotional response characterized by feelings o... More: A meta‐analysis. Journal of clinical psychology, 79(12), 2736-2767.
- Erwin, E. (2019). The concept of meaninglessness. JHU Press.
- Frankl, V. E. (1972). The feeling of meaninglessness: A challenge to psychotherapy. American Journal of Psychoanalysis, 32(1), 85.
- Heidari, M., Borujeni, M. G., & Rafiei, H. (2019). The assessment effect of spiritual care on hopelessness and depression in suicide**Suicide can be defined as “the deliberate act of ending ... More attempts. Journal of religion and health, 58(4), 1453-1461.
- Israeli, N. (2020). Meaning and meaninglessness of the self. In Re-Visioning Existential Therapy (pp. 227-236). Routledge.
- Kovalenko, O. H., & Spivak, L. M. (2018). Psychological well-being of elderly people: The social factors. Social Welfare: Interdisciplinary Approach, 8(1), 163-176.
- Safeekh, A. T. (2017). Understanding depression: An overview. Archives of Medicine and Health Sciences, 5(1), 107-111.
- Timothy, T. F., & Wong, P. T. (2024). Existential wellbeing may be of utmost importance to many people. Academia Mental Health and Well-Being, 1(3).
- Vanhooren, S. (2019). Struggling with meaninglessness: a case study from an experiential–existential perspective. Person-Centered & Experiential Psychotherapies, 18(1), 1-21.
- https://psicoadvisor.com/come-combattere-il-senso-di-vuoto-che-ci-portiamo-dentro-39144.html Accessed September 2025
- https://www.unobravo.com/post/senso-di-vuoto-interiore Accessed September 2025
- https://www.theway.org.uk/back/433corella.pdf?utm_source=chatgpt.com Accessed September 2025
- Photo by Freepik
Be part of the change. Sharing content responsibly is a gesture that stands for sustainability.
Let’s train emotional intelligenceThe first definition of Emotional Intelligence as such was p... More: what emotion does this article evoke in you?
You might be interested in
Search by category

